Introduction to the simulated moving bed chromatography principle. Dr. Paul Pietsch explains the SMB theory for beginners. Because of its continuous operation, in SMBC the columns are used much more efficiently than in a comparable batch HPLC. Binary mixtures can be separated with almost 100% yield and purity. Also up to 90% solvent can be saved and the target substance is diluted far less, than in batch HPLC.
More on SMB chromatography at https://www.knauer.net/smb
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